Archived post: posted sometime between 2016 and 2022.

Visual Studio ReSharper Performance for Large Solutions

What Really Worked

Resharper

Visual Studio

Other Helpful Things

Nuclear Option: ReSharper > Options > Code Inspection > Settings

The ultimate step is to clear the Enable code analysis check box. This will disable the design-time inspection, but you will still be able to run code inspection in the desired scope when you need it.

Turn off some VS Settings: https://github.com/dotnet/roslyn/wiki/Performance-considerations-for-large-solutions

More Visual Studio Stuff

Disable Windows Defender: https://www.tenforums.com/tutorials/5918-turn-off-windows-defender-windows-10-a.html

Tweak Windows:

R# Shortcuts Reference

Tweak ReSharper Guide